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SKU: 698983721
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During protein folding stress, the sirtuin SIRT7 also plays an important role by contributing to repressing nuclear respiratory factor 1 (NRF1) activity, a major transcriptional regulator of mitochondrial genes

Hepatology 46 , 10811090 (2007)

156 However, changes to expedite extract production such as low-speed clarification steps (S12) and the absence of the dialysis step, have changed the concentration of endogenous components in the final extract