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[2] Additional management [1] [12] Management of the underlying condition: See SIBO, Pancreatic insufficiency, and Crohn disease. Supportive care, e.g.: Avoidance of PPIs in patients with pernicious anemia [7] Neurological rehabilitation: See Treatment of polyneuropathy. RBC transfusion for anemia-related cardiac symptoms, e.g., angina pectoris, dyspnea [1] [12] In combined vitamin B 12 and folate deficiency, folate supplementation without vitamin B 12 replacement may exacerbate neurological symptoms, likely due to ongoing damage from untreated vitamin B 12 deficiency

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On the other hand, carnitine has a higher recognition for the therapeutic effect in chronic hepatitis C (CHC)

Aryl-hydrocarbon receptor-dependent alteration of FAK/RhoA in the inhibition of HUVEC motility by 3-methylcholanthrene

Recent findings indicate that 7nAChR activation may cause pathological angiogenesis in diabetic retinopathy by boosting VEGF expression [310, 311]

doi: 10.1159/000048225 99