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These parameters include a waist circumference that exceeds 40 inches in men or 35 inches in women, blood pressure that surpasses 130/85 mmHg, fasting triglyceride levels that exceed 150 mg/dL, fasting high-density lipoprotein (HDL) cholesterol levels below 40 mg/dL in men or 50 mg/dL in women, and fasting blood sugar levels that exceed 100 mg/dL (28)

Amyotrophic lateral sclerosis mutant TDP-43 may cause synaptic dysfunction through altered dendritic spine function

Incident myeloid malignancies are more common in patients whose B12 stays elevated than in those whose levels normalize