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doi: 10.3109/10717544.2014.907372 231

All cell lines were cultured according to the manufacturers instructions

Cytokines secreted by IL-2-activated lymphocytes induce endogenous nitric oxide synthesis and apoptosis in macrophages

For example, Brenton et al

These findings suggest that while high doses of rhamnetin may pose risks, its therapeutic potential can be safely harnessed when administered within an appropriate dosing regimen [113]