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doi:10.1021/bi0118557 ^ a b Perham R.N

The capacity for GSH synthesis is insufficient to maintain GSH concentrations when tissues are exposed to certain drugs or their metabolites (e.g., acetaminophen), redox cycling compounds (e.g., menadione), peroxides (e.g., tertbutyl hydroperoxide), X-rays, or ultraviolet radiation

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Intracellular ROS, measured as fluorescence by 2,7-dichlorodifluorescein diacetate (DCFDA), was associated with exposure to aspartame at 0.1 mM (100 M), a non-cytotoxic concentration

An additional consideration regarding quercetin concerns its structural classification as a pan-assay interference compound (PAINS)

These enzymatic processes assist in controlling ROS levels and preserving cellular homeostasis