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Lack of glutamine attenuated the growth of two types of intestinal epithelial cells, IEC-6 and Caco-2 in culture in vitro , which was reversed by the addition of nucleosides suggesting the role of glutamine amide nitrogen pool for the synthesis of nucleotide and glucosamine in the intestinal mucosa (46)

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For the colitis score, the weight loss rate, stool hardness, and anal bleeding were quantified as shown in Table 1