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The effects that sit outside the trial tables Menstrual-cycle changes are widely discussed in patient communities, including irregular or doubled cycles during rapid loss. Trials did not pre-specify them, so the adverse-event tables cannot estimate incidence

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receives funding from the European Research Council (ERC-CoG Trusted no.101044445), the German Research Foundation (DFG TRR296, TRR152, SFB1123 and GRK 2816/1) and the German Center for Diabetes Research (DZD e.V.)