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amides are relatively unreactive under physiological conditions, even less than similar compounds such as esters

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This change triggers the endothelial cell apoptosis, vessel regression, and blood flow reduction in the CL ( 3 Epigenetic regulation of corpus luteum function In addition to genetic and signaling pathways, epigenetic mechanisms act as key integrators of hormonal and metabolic signals, ensuring coordinated regulation of corpus luteum function

doi: 10.1055/s-2007-1002170 [DOI] [PubMed] [Google Scholar] 99.Fujimoto S, Indo Y, Higashi A, Matsuda I, Kashiwabara N, Nakashima I

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