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Results: The prevalence of frailty, sarcopenia, or both sarcopenia/frailty among the 34,405 LT recipients was 64.1%, 36.7% and 29.1% respectively

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Also, crosstalk with other signaling pathways such as transforming growth factor-beta (TGF-) has led to carcinogenesis and resistance to targeted therapies in human lung, pancreatic, and breast tumor xenografts [17]

Published evidence is limited by small numbers of patients and variability in patient selection, surgical methods and outcome reporting