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Materials and methods Bacterial cultivation and RNA purification Strains CM4 and DM4 were grown aerobically in 1.2L Erlenmeyer flasks closed with gas-tight screw caps with Mininert valves (Supelco) in Methylobacterium mineral medium (M3) (modified as described in Roselli et al., 2013), with shaking (120 rpm) at 30C