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Li W, Lu Y (2018) Hepatoprotective Effects of Sophoricoside against Fructose-Induced Liver Injury via Regulating Lipid Metabolism, Oxidation, and Inflammation in Mice

Reduced glutathione levels improved in erythrocytes, plasma, lymphocytes and buccal cells in only 1 month

ROS also activate microglia and astrocytes via p38MAPK/NF-B and JAK2/STAT3 pathways, inducing pro-inflammatory cytokine production and disrupting the neuronal microenvironment, exacerbating OS and cell death (Linnerbauer et al., 2020