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Therefore, alternative approaches are being pursued, such as modulating the activity or expression of glutamate transporters

Mutations and single nucleotide polymorphisms in genes involved in both innate and adaptive immunity and non-immune genes increase the risk of vitiligo

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Inhibited autophagy by mTOR activation in Alzheimers diseases results in damaged cellular organelles such as mitochondria and accumulation of aggregated misfolded proteins which can cause inhibition of normal cellular processes and finally neuronal cell death (Butterfield and Halliwell 2019)