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Tumor suppression by a rationally designed reversible inhibitor of methionine aminopeptidase-2

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In an in vivo test, orthotopic transplanted colon tumor model mice were randomly divided into negative control, positive control (25 mg/kg of 5-FU), low dose group (100 mg/kg of baicalin) and high dose group (200 mg/kg baicalin), respectively

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The thyroid gland expresses various selenoproteins, including DIO1, DIO2, GPX1, GPX3, GPX4, TrxR1, TrxR2, TrxR3, as well as selenoprotein F, selenoprotein P, and selenoprotein M [131]