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10.1016/j.arr.2023.101871 Ageing Res Rev 146 LiY.XieZ.LuoX.WangX.WangY.GuoM.et al (2023)

On a related note, transcriptome analyses revealed that S

Overall, recognizing these symptoms early can guide interventions that bolster the bodys antioxidant defenses

Glutathione (GSH) is the highest concentration non-protein thiol in mammalian cells and is present in concentrations of 0.5 to 10 mM

this competition, however does not prevent much smaller substrates, such as superoxide, from accessing the catalytic site, therefore enabling the enzymes action at the physiological GSH concentrations

After normalisation for protein abundance, peptide oxidation ratios were obtained for 8681 peptides, which belonged to 3006 protein groups