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Based on this finding, two incretin-based medications were developed: (1) DPP-4 inhibitors that increase the concentration of GLP-1 by inhibiting it [22], and (2) GLP-1RAs, which act directly on the GLP-1 receptor [23]

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Cells were collected by scraping into PBS and centrifuged for 10 min at 500 g

doi: 10.1016/j.neuron.2013.12.026 225 TodorovicC.SherrinT.PittsM.HippelC.RaynerM.SpiessJ