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Briefly, HPV-induced inflammation causes ROS production, which damages host and viral DNA and leads to double-strand breaks

The fits were compared to the data and both visual comparisons and calculated AICs revealed very good fits

2009 Aug;161(2):419-426

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Lu D, Choi MY, Yu J, Castro JE, Kipps TJ, Carson DA

Brennan MB, Huang ES, Lobo JM, Kang H, Guihan M, Basu A, Sohn MW