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The researchers identified the enzyme as an NADPH-dependent reductase that catalyzes a two-step reduction pathway, beginning with the conversion of curcumin to dihydrocurcumin and subsequently to tetrahydrocurcumin as the final product [22]

Siegel-Ramsay, L

These findings suggest that selenomethionines anti-ferroptosis activity may, in part, depend on its incorporation into newly synthesized proteins

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This is primarily through activation of AMPK (AMP-activated protein kinase)

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