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Iron-induced local complement component 3 (C3) up-regulation via non-canonical transforming growth factor (TGF)-beta signaling in the retinal pigment epithelium

demonstrated the beneficial effects of the conditioned medium of bovine AT-MSCs in a co-culture system with GCs for in vitro bovine embryo production, also inducing the upregulation of G6PDH and POU5F1, a key transcription factor associated with pluripotency maintenance in mammals (142, 143)

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The aim was to determine if competition for these binding sites could potentially protect the protein from glycation/oxidation factors 59

Eutopic versus ectopic comparison often led to a high number of DMPs/DMRs which may be skewed by cell-type proportions

doi: 10.1016/j.rmed.2021.106420 49 ErkelensMNGoverseGKonijnTMolenaarRBeijerMRVan den BosscheJet al