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4.3 Mitophagy and metabolic-associated fatty liver diseases Metabolic associated fatty liver disease (MAFLD) refers to a series of diseases caused by multi-systemic metabolic dysfunction resulting in chronic liver damage, including hepatic steatosis, NAFLD, hepatic fibrosis, liver cirrhosis, hepatocellular carcinoma, and others ( In vitro , CP upregulates the protein levels of PGC-1, PPAR, PINK1, Parkin, ATG7, and LC3I/II in free FA (FFA)-induced NAFLD cell models, activates the PINK1-Parkin signaling pathway to promote mitophagy in liver cells, and inhibits FFA-induced OS and lipid accumulation

Scientific literature Schmidbauer C, Hofsttter G

resistant to biotype GP) and Newton (susceptible to biotype GP) were planted in groups of 20 seeds per pot (4-inch in diameter) containing Promix Professional growing medium (Premier Horticulture Inc., Quakertown, PA)

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Newborn calves are an important component of livestock production worldwide, whether for breeding or meat production 2