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On average, volunteers in the retatrutide clinical trial who received the study drug rather than a placebo lost an average of 70.3 pounds over about a year-and-a-half, with more than 45% of participants losing more than 30% of their body weight

This predictable and targeted mode of action represents one of the key benefits of stem cell-derived peptides, offering regenerative potential without the procedural complexity of cell-based therapies

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Leber's hereditary optic neuropathy: This injection should be avoided in patients with this genetic eye disorder as it may worsen their condition