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Acknowledgements The authors wish to thank Maharishi Markandeshwar (Deemed to be) University, Mullana, India for all necessary facilities

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PCOS-related differentially expressed genes (DEGs) were identified from Gene Expression Omnibus (GEO)datasets, and weighted gene co-expression network analysis (WGCNA) revealed the disease-associated gene modules

Among the different NEDA parameter candidates, plasmatic biomarkers for CNS lesion are showing promising results, such as neurofilament light chain (NfL) and glial fibrillary acid protein (GFAP)