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Adv Immunol 91:175226 Hogan B, Beddington R, Costantini F, Lacy E (1994) Manipulating the mouse embryo

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Targeted sequencing approach and its clinical applications for the molecular diagnosis of human diseases

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To link oxidative stress and cardiac remodeling in DM and CKD, CKD was induced in genetically modified DM swine ( INS C94Y transgenic) at 1012 weeks of age via renal microembolization, while non-embolized DM and wild-type (WT) swine served as controls