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Epigenetic regulation in metabolic diseases: mechanisms and advances in clinical study

10.1038/labinvest.2014.69 193 ZhangZ.JiangN.NiZ

Surprisingly, one of the inducers of Gcl-c expression is 4-Hydroxynonenal (HNE), the major end product of lipid peroxidation 27,28

While our mechanistic data and mouse model results are compelling, a formal statistical causal inference or randomized controlled design would be required to definitively attribute hyperprogression to the immunotherapy regimen

doi:10.2174/138620706776055458

All concerned establishments are warned not to distribute, advertise, or sell the said violative food products and food supplements until CPR are issued, otherwise, regulatory actions and sanctions shall be strictly pursued