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Sleep Architecture and Delta-Wave Promotion: In rabbit, rat, cat, and limited human EEG studies, intravenous or intracerebroventricular DSIP administration significantly increased total sleep time, prolonged slow-wave sleep (SWS) duration, increased delta-wave power, and reduced sleep latency without altering REM sleep proportion

This outcomes in the deposit of toxic substances, such as ammonia, and the development of complications like cerebral edema and multi-organ failure [3]

IGF-1 Elevation As growth hormone levels rise, so does IGF-1 , primarily produced by the liver

*Correspondence: Ligang Tong, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

doi: 10.1038/s41423-023-01036-7

Subjects consumed 970 mg CLE capsules, containing 400 g bisacurone, 100 g turmeronol A and 100 g turmeronol B