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Pilot-study to explore metabolic signature of type 2 diabetes: a pipeline of tree-based machine learning and bioinformatics techniques for biomarkers discovery

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To improve the quality and resolution of the highly flexible catalytic domains, masked local refinement with D1 symmetry imposed with a soft mask of the most central catalytic and regulatory domains (6 dilation with a soft padding of 20 ) was used

When GPX4 activity is hindered, lipid peroxides accumulate and ultimately cause cell death