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However, it is believed to result from a combination of factors, including mitochondrial dysfunction, inhibition of bile salt export pumps, and genetic predisposition [8] (Table 1)

Regarding T-DXd toxicity, gastrointestinal and hematological events were the most common AEs of any grade, with neutropenia being the most common AE of grade 3

Pecorelli A, Leoncini S, De Felice C, Signorini C, Cerrone C, Valacchi G, et al

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