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In the cytosol, Cyt c, Apaf-1, and dATP form the apoptosome, which activates caspase-9, thereby initiating a proteolytic cascade involving effector caspases like caspase-3 (9)

Glutathione reductase (GR), an NADPH-dependent enzyme, continuously regenerates reduced glutathione (GSH) from its oxidized form (GSSG), thereby maintaining the intracellular reducing environment required for effective antioxidant defense, proper enzymatic activity, and redox-dependent signaling pathways [36]

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Lactic acid is generally better for sensitive skin due to its larger molecular size and gentler exfoliation

However, these formulations work best when used under the guidance of a trusted healthcare provider and purchased from a licensed pharmacy