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Using an untargeted NMR-based approach, we identified and quantified 44 metabolites from a total of 52 detected (Figure S1, Table S1), excluding those with poor signal quality in the H-NMR spectrum or technical artefacts such as residual methanol

Metronidazole resistance mechanisms Resistance to metronidazole (Mtz) has shown to limit the effectiveness of Mtz containing regimens [98, 99]

We have chosen prpTDP-43 A315T mice for our analyses, because this mouse model of TDP-43 pathology was generated based on the A315T mutation detected in the TARDP gene of ALS patients, who had TDP-43 pathology in their cortex 19 , and because the mouse model strictly recapitulated many aspects of the disease, including progressive CSMN degeneration 16

Huang et al., 2000a)

Nikon A1R confocal microscope (Nikon, Japan) was applied to generate 3D rendered videos

Ma HY, Xu J, Liu X, Zhu Y, Gao B, Karin M, et al