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Aghdaei, H

Unlike the peripheral nervous system, which transmits signals throughout the body, the CNS relies on the BBB to maintain a stable environment for neural function

This index was significantly lower, not exceeding 30%, in the case of monotherapy, except for the OV1946 cell line, where the percentage was approximately 60% for ABT-263 and about 50% for olaparib [137]

To investigate this potential release, NP4 was incubated with phosphate-buffered saline (PBS) or PBS containing H 2 O 2 as a model for ROS inside the cancer cells and the release monitored by ICP-MS

Human trials are small, but results have been promising

The CD4 + T-cell-specific deletion of ASCT2 significantly suppressed the immune response of Th1 and Th17 cells in a mouse EAE model (81)