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In addition, increased ketone body levels increase flux through mitochondrial beta-hydroxybutyrate dehydrogenase 1 (BDH1) that reduces the mitochondrial [NAD + ]/[NADH] leading to increased ETC activity (Opii et al., 2008)

Statin use and the risk of colorectal cancer in a population-based electronic health records study

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Because, in a typical cell, secretory and membrane proteinsi.e., ER client proteinscomprise approximately one-third of the total cellular proteome , increased nutrient catabolism portends an imminent demand on the ER biosynthetic capacity

De Vriese C, Gregoire F, Lema-Kisoka R, Waelbroeck M, Robberecht P, Delporte C