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The synaptic accumulation and misfolding of alpha-synuclein is considered a pathological hallmark and propagates in a prion-like fashion through interconnected neural circuits [8, 9]

Driscoll MS, Kwon EK, Skupsky H, Kwon SY, Grant-Kels JM

Moreover, until 6 h the red fluorescence remained intact after which they became dotted, which indicated the breakage and release of DOX into cytoplasm

Multiple human and preclinical studies suggest that NAD+ precursors such as NMN and NR may influence energy metabolism, vascular function, and cellular stress responses

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There was a positive correlation between the levels of hippocampal tCho, mI and Cr with the overall severity of mood symptoms (total DASS-21 scores), as well as the levels for each domain, depression, anxiety and stress ( Table 3 ), while Glx levels showed an association with anxiety levels