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Pediatric patients who suddenly develop OCD, vocal or motor tics, rage episodes, separation anxiety, or behavioral regression, particularly following an infection, should be evaluated for PANS/PANDAS and mast cell activation

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70 Nevertheless, PSA responses together with molecular changes in CTCs identified 3 responders (1-03, 2-01, and 2-07), who were all on the combination treatment for multiple cycles and shared several common characteristics

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Apr 1992;31(4):444-8

They at least have a body of Russian clinical trials in stroke, cognitive disorders, and anxiety