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and El Moukhtari et al

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In children with ASD with gastrointestinal problems, implementation of a specific carbohydrate diet protocol has not been evaluated but is an intervention commonly used by many families without clinical guidance

Another point to be considered is that etomoxir needs to be converted to its acyl-CoA derivative, etomoxiryl-CoA to exert its inhibitory activity, but the specific enzyme responsible for this conversion in mammals has not been identified thus far, partly due to the lack of a crystal of CPT1 with bound etomoxir (Selby and Sherratt, 1989

Conclusion and perspectives Mitochondria are masters of energy conservation

10.1016/j.jhep.2017.11.014 J Hepatol