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Frataxin deficiency leads to defects in expression of antioxidants and Nrf2 expression in dorsal root ganglia of the Friedreichs ataxia YG8R mouse model

4 Biochemical studies of the 1970s on dopamine receptors, which were based on second messenger assays (e.g

BecchiPPRocchettiGGarca-PrezPMicheliniSPizzamiglioVLuciniL

WIPO patent WO2006129623A1 (2006)

As for UGT74F2, while each individual mutation (T365A or T15S) did not significantly affect the activity, compared to the wild-type UGT74F2, the double mutant UGT74F2 T15S, T365A displayed an 85% decrease in activity for SGE production (Fig