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In a PCPA-induced insomnia mouse model, DSIP-CBBBP outperformed DSIP alonemore effectively restoring neurotransmitter balance, reducing wakefulness, easing anxiety and depression-like behaviors, improving reward response, and repairing brain tissue damage

Peptide solution storage: pH should be as acidic as possible, such as 5-6, -20C, and sterilized buffer solution should be used

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10.1016/j.tins.2007.01.002 49 KobelM.BechtelN.WeberP.SpechtK.KlarhoferM.SchefflerK.et al