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9 Controversies in astrocyte-neuron metabolic coupling: the lactate shuttle and alternative viewpoints A significant and ongoing debate in brain energy metabolism centers on the quantitative importance and primary pathway of fuel delivery to activated neurons

10.1038/s41569-021-00644-y 194

After separating the gel from the bottom of the wells, the diameter of the collagen gel was measured using analysis software (BZ-X800E Analyzer

Free Radic Biol Med 34:10781088 Chatterjee A (2013) Reduced glutathione: a radioprotector or a modulator of DNA-repair activity

Mutant KRAS increases the expression of glucose transporter 1 (GLUT1) and rate-limiting glycolytic enzymes, including hexokinases, phosphofructokinase 1 (PFK1), and lactate dehydrogenase A (LDHA), promoting glycolytic activity and increasing lactate production [17, 18]

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