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The approval process typically requires extensive preclinical testing followed by phased clinical trials demonstrating safety and efficacy

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Thirty-three patients (Group I) had at least one P or LP MDR3 variant, whereas the remaining patients (Group II) had none or mutations of unknown significance (VUS)

10.1016/j.biopha.2023.115319 141 SongY.FengN.YuQ.LiY.MengM.YangX.et al (2025)

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