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3 for the compound ENDO3, is independent of the Rab27a-mediated Munc13-4 function in secretion but is instead mediated by the impact of ENDOs on the STX7Munc13-4 interaction regulating CpG-mediated endosomal activation

The plasmid for h SI (NCBI NP_006570.1) expression was constructed previously 14

The analysis of binding energies showed that compounds with binding energies below 4.25 kcal/mol had possible binding activity, those with energies below 5.0 kcal/mol had stronger binding activity, and compounds with energies below 7.0 kcal/mol had considerable binding activity ( 2.13 Statistical methods Statistical analysis of the data in this study was performed using GraphPad Prism 9.0 software, and the results are expressed as the mean standard error of the mean

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This product is unflavoured, meaning no flavouring agents have been added