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Helps reduce joint pain and swelling, supports cartilage repair, and improves flexibility and mobility

High incidence of IDH mutations in acute myeloid leukaemia with cuplike nuclei

Bopp LH, Ehrlich HL (1988) Chromate resistance and reduction in Pseudomonas fluorescens strain LB300

Gastrointestinal: bowel irregularity, constipation aggravated, dyspepsia, dysphagia, dysplasia GI, epigastric pain, eructation, esophageal disorder, frequent stools, gastroenteritis, GI hemorrhage, GI symptoms not otherwise specified, hiccup, melena, mouth disorder, pharynx disorder, rectal disorder, serum gastrin increased, tongue disorder, tongue edema, ulcerative stomatitis, vomiting

Drug approval requires demonstrated efficacy plus safety

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