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The mechanisms of cachexia underlying muscle dysfunction in COPD

In ISO-administered rats, renal sections showed hyaline deposits, tubular brush boundary loss, and mononuclear cell infiltration in the kidney cortex (Fig

& Meijer, A

[PubMed Citation] Pregnant animal studies Reproductive and developmental toxicity studies performed in rats at oral doses up to 6.7 times the recommended human intravenous dose and in rabbits at doses up to 3.3 times the recommended human intravenous dose revealed no evidence of impaired fertility or embryofetal toxicity