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Molecular approaches for therapy of lung cancer, Invited Lecturer

Requires careful formulation and dissolution into aqueous or hydrating mediums (usually below pH 7)

Binding of LTC 4 to its internalized receptors then sets in motion nuclear and perinuclear translocation of NOX4, generating ROS, oxidative nuclear DNA damage, apoptosis and necrosis

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This nanosheet is quite stable in solution in a short term of several hours but can degrade and release Zn 2+ during the subsequent long-term action by fluid stress

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