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(3) One posited route involves copper bioavailability: the peptide may act as a carrier that delivers Cu(II) in a redox-silent form, with coppers oxidative activity apparently suppressed when complexed within the GHK structure

Ribeiro et al., 2017

Certain populations face higher deficiency risk: vegetarians and vegans (B12 is primarily found in animal products), adults over 50 (decreased stomach acid reduces B12 absorption), individuals with digestive disorders like Crohn's disease or celiac disease, and those taking medications like metformin or proton pump inhibitors

By dampening this pathway while supporting restorative processes, DSIP may help protect and repair neural tissue

They deliver precursors directly to the bloodstream through oral mucosa

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