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Skin hyperpigmentation and skin hypopigmentation have been reported in about 2% of patients with topical tretinoin therapy, with resolution following discontinuation of tretinoin

Treat this as conservative protocol planning

To address challenges such as inadequate permeability, diminished bioavailability, and regulatory considerations of peptides, nanotechnologies have been employed, including microneedles and liposomes

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Rights and permissions About this article Cite this article Duan, D., Goemans, N., Takeda, S

Another report from Korea by Seong et al