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For (i), the number of observations ranged between 77 to 117 trials with startle data (depending on the subcompartment) and between 72 and 109 episodes of spontaneous running, while for (ii) the number of observations ranged between 60 and 86 for the startle data and between 35 and 44 for the spontaneous runs

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FOXO3 also upregulates the expression of dynamin-related protein 1 (DRP1), mitochondrial fission 1 protein (FIS1), and mitofusin 2 (MFN2) to regulate mitochondrial fission 100