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Barbiturates (e.g., phenobarbital) induce hepatic microsomal enzymes and may impair the ability to safely metabolize Ace 125 mg, increasing NAPQI formation and hepatotoxicity risk particularly in overdose situations

Since ER transcriptionally upregulated SLC7A11 and SLC3A2 expression (Fig

Vanhaesebroeck, B., Guillermet-Guibert, J., Graupera, M

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Heat stress induced apoptosis is triggered by transcription-independent p53, Ca2+ dyshomeostasis and the subsequent Bax mitochondrial translocation

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