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With regard to haemolymphatic cells, they represent the first line of defence against pathogens and xenobiotics and can be considered suitable biomarkers for monitoring the effects of environmental stress ( M

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However, their contribution is context-dependent, as genetic ablation of ABCC1 does not fully prevent apoptosis-associated GSH loss in certain models 43 , indicating the existence of compensatory or alternative efflux mechanisms

Zhang et al., 2018b)

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