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Number of Coats: Oil-based finishes require fewer coats than water-based

This primary configurational difference at the C-20 position makes the -methoxyacrylate group in speciogynine and paynantheine perpendicular to the molecules plane, whereas the substituent at C-20 in mitragynine is planar (see Figure 3)

We will also discuss advanced delivery methods designed to overcome these barriers

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