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This process is coordinated by glutamate ammonia ligase (GLUL), a cytosolic enzyme that catalyzes glutamine synthesis from glutamate and ammonium ions (NH 4 + )

[DOI] [PMC free article] [PubMed] [Google Scholar] 34.Chen X., Zhang S., Wang Z., Wang F., Cao X., Wu Q., Zhao C., Ma H., Ye F., Wang H., Fang Z., Supervillin promotes epithelial-mesenchymal transition and metastasis of hepatocellular carcinoma in hypoxia via activation of the RhoA/ROCK-ERK/p38 pathway

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The following validation parameters were determined for the developed method: Precision, Accuracy, Linearity, Specificity, Ruggedness (Intermediate Precision) and Robustness, as per the ICH guidelines