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[12] It is still controversial whether oral supplementation for glutathione works well or not

As an illustrative analogy for counteraction of the opposite effects of L-NAME and L-arginine in haemorrhage, we should emphasize that the particular effects of BPC 157 on blood pressure [18,20,25] and the anti-arrhythmic effect [1821] include antagonization of both L-NAME (hypertension) and L-arginine (hypotension) [25] and counteraction of endothelin serum increase [20]

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Glutathione, the sole active ingredient, is a tripeptide composed of glutamine, cysteine, and glycine, and is recognized for its critical role in cellular defense against oxidative stress, as well as its involvement in numerous metabolic and detoxification pathways

Beyond its key role in skeletal homeostasis, several recent studies suggest extra-skeletal effects, such as a role as an immunomodulator in both adaptive and innate immune responses [102]