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NET-containing guanylated peptides can be internalized by FLSs through the TLR9 pathway, elevating the inflammatory phenotype of FLSs and upregulating the expression of major histocompatibility complex class II molecules, which subsequently produce autoantibodies by presentation to Ag-specific T-cells (168)

outcomes vary

Development of nucleic acid medicines based on chemical technology

Samples were incubated for 1 h under microaerobic conditions with shaking

More serious concerns require careful monitoring but affect only a small percentage of patients

Synergistic inhibition of oxidation of phosphatidylcholine liposomes in acqueous dispersions by Vitamin E and Vitamin C